Description

2-Oxaspiro[4.4]Nonan-3-One, 4-Hydroxy-, (4S)- (9Ci) is a high-value chiral spirocyclic compound, a key synthetic intermediate prized for its complex stereochemistry and functional group arrangement. Its precise stereocenter and unique spirocyclic scaffold make it an essential building block for the synthesis of advanced pharmaceutical agents and complex organic molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.
• Agrochemical Synthesis: Used as a building block in the development of advanced pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity.
• Fine Chemical Production: Serves as a key starting material or intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: Employed in chemical research for methodology development, catalysis studies, and the exploration of new spirocyclic compound libraries.
• Material Science Precursor: Potential use in the synthesis of specialized monomers or ligands for advanced polymeric materials and catalysts.

Basic Information

Item	Details
Product Name	2-Oxaspiro[4.4]Nonan-3-One, 4-Hydroxy-, (4S)- (9Ci)
CAS No.	697290-52-1
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(4S)-4-Hydroxy-2-oxaspiro[4.4]nonan-3-one; (4S)-4-Hydroxy-2-oxaspiro[4.4]nonane-3-one; 4-Hydroxy-2-oxaspiro[4.4]nonan-3-one, (4S)-; (S)-4-Hydroxy-2-oxaspiro[4.4]nonan-3-one; 2-Oxaspiro[4.4]nonane-3-one, 4-hydroxy-, (4S)-; Spirocyclic γ-lactone derivative; (4S)-4-Hydroxyspiro[4.4]nonane-1,3-dione (tautomeric form)
EINECS	Contact for details

Quality Control

Our production of 2-Oxaspiro[4.4]Nonan-3-One, 4-Hydroxy-, (4S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.