Description

Pentanoic Acid, 5-Oxo-5-(2-Propyn-1-Ylamino)-, 2,5-Dioxo-1-Pyrrolidinyl Ester is a specialized chemical building block featuring a unique combination of an activated ester and an alkyne-functionalized amide. This bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in the development of novel pharmaceutical compounds and functional materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring selective conjugation and derivatization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, leveraging its reactive ester and alkyne groups for click chemistry and bioconjugation.
• Bioconjugation Reagent: Used to functionalize biomolecules such as peptides, proteins, and antibodies for drug delivery systems, diagnostics, and targeted therapies.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers with tailored properties, including hydrogels and smart materials.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in surface modification and the creation of functional coatings and adhesives.
• Chemical Biology Probes: Enables the synthesis of probes for studying enzyme activity and cellular processes.

Basic Information

Product Name	Pentanoic Acid, 5-Oxo-5-(2-Propyn-1-Ylamino)-, 2,5-Dioxo-1-Pyrrolidinyl Ester
CAS No.	693777-85-4
Molecular Formula	C12H12N2O5
Molecular Weight	264.24 g/mol
Synonyms	5-Oxo-5-(prop-2-yn-1-ylamino)pentanoic acid 2,5-dioxopyrrolidin-1-yl ester; N-(2-Propynyl)-5-[(2,5-dioxo-1-pyrrolidinyl)oxy]-5-oxopentanamide; N-Propargyl-5-[(2,5-dioxo-1-pyrrolidinyl)oxy]-5-oxopentanamide; N-Propargylglutaramide N-hydroxysuccinimide ester; Propargyl-PEG4-NHS ester (related analog); Activated Alkyne Ester; Succinimidyl propargyl glutarate
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 5-Oxo-5-(2-Propyn-1-Ylamino)-, 2,5-Dioxo-1-Pyrrolidinyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.