Description

Cyclopropanecarboxylic Acid, 2-[(Phenylmethoxy)Methyl]-, Ethyl Ester, (1S,2S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique cyclopropane ring fused with a benzyl-protected oxygen functionality, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise stereochemistry is paramount for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the cyclopropane moiety can enhance stability and bioactivity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in studies exploring new catalytic methodologies for stereoselective synthesis.
• Material Science Precursor: Acts as a starting material for synthesizing specialized monomers or ligands used in advanced polymers and metal-organic frameworks (MOFs).
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-[(Phenylmethoxy)Methyl]-, Ethyl Ester, (1S,2S)-
CAS No.	692778-41-9
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	(1S,2S)-Ethyl 2-[(Benzyloxy)methyl]cyclopropanecarboxylate; (1S,2S)-2-(Benzyloxymethyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl (1S,2S)-2-[(Phenylmethoxy)methyl]cyclopropanecarboxylate; (1S,2S)-Rel-2-[(Phenylmethoxy)methyl]cyclopropanecarboxylic Acid Ethyl Ester; (1S-cis)-2-[(Benzyloxy)methyl]cyclopropanecarboxylic Acid Ethyl Ester; BOC Sciences Brand Name BLD-692778; Chiral Cyclopropane Ester Derivative.
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-[(Phenylmethoxy)Methyl]-, Ethyl Ester, (1S,2S)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including Chiral HPLC for enantiomeric excess (ee) verification and NMR for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.