Description

Acetamide, n-(Acetyloxy)-n-(Trimethylsilyl)- is a specialized organosilicon reagent featuring a unique acetamide core functionalized with acetyloxy and trimethylsilyl groups. This compound is valued for its role as a versatile synthetic intermediate and protecting group agent in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing or protecting sensitive functional groups.
• Agrochemical Synthesis: Serves as a key building block in the development of novel herbicides, fungicides, and insecticides.
• Silicon Chemistry Reagent: Acts as a silylating agent or precursor in organosilicon chemistry for material science applications.
• Peptide & Nucleotide Chemistry: Employed in the protection of amines or hydroxyl groups during the synthesis of peptides and nucleotide analogs.
• Polymer Modification: Utilized to introduce functional silane groups into polymer backbones to alter material properties.
• Chemical Research: A valuable tool in academic and industrial R&D for methodology development and exploratory synthesis.

Basic Information

Product Name	Acetamide, n-(Acetyloxy)-n-(Trimethylsilyl)-
CAS No.	692753-01-8
Molecular Formula	C7H15NO3Si
Molecular Weight	189.28 g/mol
Synonyms	N-(Acetyloxy)-N-(trimethylsilyl)acetamide; N-Acetoxy-N-(trimethylsilyl)acetamide; Acetamide, N-(acetyloxy)-N-(trimethylsilyl)-; N-(Trimethylsilyl)acetoxyacetamide; TMS-acetoxyacetamide; (Acetyloxy)(trimethylsilyl)amino]ethanone; N-Acetoxy-N-trimethylsilylacetamide
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-(Acetyloxy)-n-(Trimethylsilyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) documenting all relevant specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.