Description

5-Bromo-n-{4-[(Isopropylamino)Sulfonyl]Phenyl}Nicotinamide is a high-purity, advanced pharmaceutical intermediate with a distinct sulfonamide-linked nicotinamide core. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly in medicinal chemistry research and development. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the development of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe to study enzyme inhibition or receptor binding mechanisms.
• API Development: A key starting material or intermediate in the development and scale-up of Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	5-Bromo-n-{4-[(Isopropylamino)Sulfonyl]Phenyl}Nicotinamide
CAS No.	692746-37-5
Molecular Formula	C15H16BrN3O3S
Molecular Weight	398.28 g/mol
Synonyms	5-Bromo-N-[4-[(propan-2-ylamino)sulfonyl]phenyl]pyridine-3-carboxamide; 5-Bromo-3-pyridinecarboxamide, N-[4-[(isopropylamino)sulfonyl]phenyl]-; N-(4-(Isopropylsulfamoyl)phenyl)-5-bromonicotinamide; 5-Bromo-N-(4-(N-isopropylsulfamoyl)phenyl)nicotinamide; 692746-37-5; 5-Bromo-nicotinamide derivative; Isopropylamino sulfonyl phenyl nicotinamide bromo derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-{4-[(Isopropylamino)Sulfonyl]Phenyl}Nicotinamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.