Description

5-Bromo-n-{4-[(Ethylamino)Sulfonyl]Phenyl}Nicotinamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct sulfonamide and nicotinamide functional groups. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel bioactive molecules targeting specific enzyme pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity in new chemical entities.
• Biochemical Reagent: Serves as a reference standard or a substrate analog in enzymatic assays and biochemical studies.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce specific bromo and sulfonamide functionalities into complex molecules.

Basic Information

Product Name	5-Bromo-n-{4-[(Ethylamino)Sulfonyl]Phenyl}Nicotinamide
CAS No.	692746-20-6
Molecular Formula	C14H14BrN3O3S
Molecular Weight	384.25 g/mol
Synonyms	5-Bromo-N-[4-(ethylsulfamoyl)phenyl]pyridine-3-carboxamide; 5-Bromo-3-pyridinecarboxamide, N-[4-[(ethylamino)sulfonyl]phenyl]-; Nicotinamide, 5-bromo-N-[4-[(ethylamino)sulfonyl]phenyl]-; 692746-20-6; 5-Bromo-N-(4-(ethylsulfamoyl)phenyl)nicotinamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-{4-[(Ethylamino)Sulfonyl]Phenyl}Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.