Description

Morpholine, 4-(2-Fluoroethyl)- (9Ci) is a fluorinated derivative of morpholine, a versatile heterocyclic amine, designed for advanced chemical synthesis. This compound is valued for its unique combination of a morpholine scaffold with a fluoroethyl side chain, offering specific reactivity and physicochemical properties for creating novel molecular architectures. It serves as a critical building block for researchers and process chemists in the pharmaceutical and agrochemical industries, where the introduction of fluorine atoms is a key strategy to modulate the biological activity, metabolic stability, and lipophilicity of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine moiety can enhance product efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in asymmetric catalysis or as a component in organocatalysts.
• Material Science Research: Employed in the synthesis of functionalized polymers, dyes, or liquid crystals where the morpholine and fluorine groups impart specific material properties.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging, diagnostics, and studying biological mechanisms.

Basic Information

Product Name	Morpholine, 4-(2-Fluoroethyl)- (9Ci)
CAS No.	691905-88-1
Molecular Formula	C6H12FNO
Molecular Weight	133.16 g/mol
Synonyms	4-(2-Fluoroethyl)morpholine; N-(2-Fluoroethyl)morpholine; 2-Fluoroethylmorpholine; Morpholine, N-(2-fluoroethyl)-; 4-(2-Fluoroethyl)-morpholine; 2-Fluoroethyl morpholine; N-(2-Fluoroethyl)-morpholine; 4-(β-Fluoroethyl)morpholine
EINECS	Contact for details

Quality Control

Our production of Morpholine, 4-(2-Fluoroethyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product may be stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.