Description

6-Bromospiro[Chromene-2,4'-Piperidin]-4(3H)-One Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and building block used in modern organic synthesis. This compound is valued for its unique spirocyclic and brominated chromene structure, which is critical for imparting specific biological activity and physicochemical properties in target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry.
• Process Chemistry & Scale-Up: Acts as a critical intermediate during the process development and pilot-scale manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	6-Bromospiro[Chromene-2,4'-Piperidin]-4(3H)-One Trifluoroacetate
CAS No.	690632-09-8
Molecular Formula	C16H15BrF3NO3
Molecular Weight	406.20 g/mol
Synonyms	6-Bromo-3H-spiro[1-benzopyran-2,4'-piperidin]-4-one trifluoroacetate; 6-Bromospiro[chromene-2,4'-piperidin]-4(3H)-one TFA salt; 6-Bromo-4-oxospiro[chromene-2,4'-piperidine] trifluoroacetate; 6-Bromospiro[benzopyran-2,4'-piperidin]-4-one trifluoroacetate; 6-Bromo-3H-spiro[chromene-2,4'-piperidin]-4-one TFA; 6-Bromo-4-oxo-3H-spiro[1-benzopyran-2,4'-piperidine] trifluoroacetate; TFA salt of 6-Bromospiro[chromene-2,4'-piperidin]-4(3H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[Chromene-2,4'-Piperidin]-4(3H)-One Trifluoroacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities, ensuring reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.