Description

6-Bromospiro[Chroman-2,4'-Piperidin]-4-One is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-up: Serves as a critical material for route scouting, optimization, and pilot-scale production of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of other complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	6-Bromospiro[Chroman-2,4'-Piperidin]-4-One
CAS No.	690632-08-7
Molecular Formula	C13H14BrNO2
Molecular Weight	296.16 g/mol
Synonyms	6-Bromospiro[chroman-2,4'-piperidin]-4-one; 4H-Spiro[chromene-2,4'-piperidin]-4-one, 6-bromo-; 6-Bromo-4H-spiro[chromene-2,4'-piperidin]-4-one; 6-Bromo-1-azaspiro[4.5]decan-7-one; 6-Bromo-1-azaspiro[4.5]decan-7-one (related structure); Spiro[chroman-2,4'-piperidin]-4-one, 6-bromo-; CAS 690632-08-7
EINECS	Contact for details

Quality Control

Our 6-Bromospiro[Chroman-2,4'-Piperidin]-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.