Description

(R)-1-(5-Bromo-Pyridin-2-Yl)-Pyrrolidin-3-Ol is a high-purity chiral building block featuring a brominated pyridine core and a pyrrolidin-3-ol moiety. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for creating new active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A potential precursor for advanced organic electronic materials due to its conjugated pyridine system.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific bromo-functionalized chiral pyrrolidines.

Basic Information

Product Name	(R)-1-(5-Bromo-Pyridin-2-Yl)-Pyrrolidin-3-Ol
CAS No.	690265-87-3
Molecular Formula	C9H11BrN2O
Molecular Weight	243.10 g/mol
Synonyms	(R)-1-(5-Bromopyridin-2-yl)pyrrolidin-3-ol; (3R)-1-(5-Bromo-2-pyridinyl)-3-pyrrolidinol; (R)-1-(5-Bromo-2-pyridyl)pyrrolidin-3-ol; 5-Bromo-2-[(3R)-3-pyrrolidinyloxy]pyridine; 690265-87-3; (R)-3-Hydroxy-1-(5-bromopyridin-2-yl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Bromo-Pyridin-2-Yl)-Pyrrolidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.