Description

4-(4-Thiazolyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine-thiazole hybrid structure. This compound is of significant value in medicinal chemistry for constructing novel molecular scaffolds, particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and fine chemical industries engaged in drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for the production of specialized fine chemicals and APIs.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry and methodology development.

Basic Information

Product Name	4-(4-Thiazolyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	690261-82-6
Molecular Formula	C13H20N2O2S
Molecular Weight	268.37 g/mol
Synonyms	tert-Butyl 4-(thiazol-4-yl)piperidine-1-carboxylate; 1-Boc-4-(4-thiazolyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(thiazol-4-yl)piperidine; 4-(1-Boc-piperidin-4-yl)thiazole; 4-(Thiazol-4-yl)piperidine-1-carboxylic acid tert-butyl ester; 4-(4-Thiazolyl)-1-piperidinecarboxylic acid tert-butyl ester; 690261-82-6; Boc-4-(4-thiazolyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Thiazolyl)-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.