Description

3-(Piperidin-4-Yl)Pyridine Hydrochloride is a high-purity, versatile heterocyclic building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its unique fused piperidine-pyridine scaffold, which is a privileged structure for modulating biological activity and physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting neurological receptors and enzymes.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries due to its versatile piperidine-pyridine core.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for metal catalysis and in the preparation of organocatalysts.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-(Piperidin-4-Yl)Pyridine Hydrochloride
CAS No.	690261-73-5
Molecular Formula	C10H15ClN2
Molecular Weight	198.69 g/mol
Synonyms	4-(3-Pyridinyl)piperidine hydrochloride; 3-(4-Piperidinyl)pyridine hydrochloride; 4-Pyridin-3-ylpiperidine hydrochloride; Pyridine, 3-(4-piperidinyl)-, hydrochloride; 3-Pyridin-4-ylpiperidine hydrochloride (isomer); 4-(Pyridin-3-yl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture from the air, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.