Description

3-Bromo-5-Iodo-Benzoic Acid tert-Butyl Ester is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists requiring precise, site-specific functionalization in complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated structure.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira cross-coupling reactions due to the presence of both bromo and iodo substituents, allowing for sequential functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Bromo-5-Iodo-Benzoic Acid tert-Butyl Ester
CAS No.	690260-92-5
Molecular Formula	C11H12BrIO2
Molecular Weight	383.02 g/mol
Synonyms	tert-Butyl 3-bromo-5-iodobenzoate; Benzoic acid, 3-bromo-5-iodo-, 1,1-dimethylethyl ester; 3-Bromo-5-iodobenzoic acid 1,1-dimethylethyl ester; 3-Bromo-5-iodo-benzoic acid tert-butyl ester; tert-Butyl 3-bromo-5-iodobenzoate; 690260-92-5; BIBE (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Iodo-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.