Description

6-Iodo-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for the development of novel active ingredients. Pharmaceutical R&D teams and fine chemical manufacturers need it to create potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its fused triazolopyridine core.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands and functional organic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	6-Iodo-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	690257-94-4
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	6-Iodo-[1,2,4]triazolo[4,3-a]pyridine; 6-Iodo-1,2,4-triazolo[4,3-a]pyridine; 6-Iodotriazolopyridine; 690257-94-4; Triazolo[4,3-a]pyridine, 6-iodo-; 6-Iodo-1H-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Iodo-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.