Description

3-Piperidinamine,4-Ethyl-,(3R,4S)-Rel-(9Ci) is a chiral piperidine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs), where stereochemical purity is critical for efficacy and safety. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for creating novel, stereospecific agrochemicals such as herbicides and fungicides with improved activity profiles.
• Academic & Industrial R&D: Employed in chemical research laboratories for methodological studies in stereoselective synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules under cGMP conditions.

Basic Information

Product Name	3-Piperidinamine,4-Ethyl-,(3R,4S)-Rel-(9Ci)
CAS No.	688736-27-8
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	(3R,4S)-4-Ethyl-3-piperidinamine; rel-(3R,4S)-4-Ethylpiperidin-3-amine; 4-Ethyl-3-piperidinamine (rel-(3R,4S)-); 3-Amino-4-ethylpiperidine (stereoisomer); (3R,4S)-4-Ethyl-3-aminopiperidine; 688736-27-8; 4-Ethylpiperidin-3-amine (specific stereoisomer)
EINECS	Contact for details

Quality Control

Our production of 3-Piperidinamine,4-Ethyl-,(3R,4S)-Rel-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity, critical for pharmaceutical applications. All materials are fully characterized, and production can be aligned with current Good Manufacturing Practice (cGMP) principles for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.