Description

Fmoc-Val-Osu CAS NO 688585-20-8 is a high-purity, activated ester derivative of the amino acid valine, protected with a 9-fluorenylmethoxycarbonyl (Fmoc) group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the efficient and controlled incorporation of valine residues into peptide chains. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, diagnostic agents, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the automated, stepwise synthesis of peptides using Fmoc-chemistry protocols.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation: Facilitates the site-specific labeling of proteins, antibodies, or other biomolecules with valine-containing tags or probes.
• Combinatorial Chemistry: Employed in the generation of peptide libraries for high-throughput screening in drug discovery.
• Academic & Industrial Research: Serves as a fundamental tool for studying protein structure-function relationships and developing novel bioactive compounds.
• Custom Peptide Service Providers: A staple raw material for CROs and CDMOs offering bespoke peptide synthesis services.

Basic Information

Product Name	Fmoc-Val-Osu
CAS No.	688585-20-8
Molecular Formula	C24H24N2O6
Molecular Weight	436.46 g/mol
Synonyms	Fmoc-L-Valine N-hydroxysuccinimide ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine N-succinimidyl ester; Fmoc-Val-OSu; Fmoc-Valine-OSu ester; N-Fmoc-L-valine succinimidyl ester; Nα-Fmoc-Nω-OSu-L-valine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanoic acid 2,5-dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Val-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive applications like pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -15°C under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.