Description

Xanthohumol L CAS NO 688360-15-8 is a purified, prenylated chalconoid compound primarily isolated from hops (Humulus lupulus). This high-purity grade is valued for its potent biological activity and serves as a key reference standard and active ingredient. It is essential for research and development in the nutraceutical, pharmaceutical, and cosmetic industries. Our product is supplied with comprehensive analytical documentation to ensure traceability and batch-to-batch consistency for demanding B2B applications.

Application

• Nutraceutical & Dietary Supplement Formulation: Used as a bioactive ingredient in capsules, tablets, and liquid extracts targeting antioxidant support, metabolic health, and inflammation management.
• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in preclinical studies for its potential anti-cancer, anti-angiogenic, and antiviral properties.
• Cosmetic & Personal Care Actives: Incorporated into advanced skincare formulations for its antioxidant and potential anti-aging benefits, protecting skin from environmental stressors.
• Functional Food & Beverage Fortification: Utilized to enhance the health profile of specialized food and beverage products, including health drinks and sports nutrition.
• Analytical & Quality Control Laboratories: Employed as a high-purity certified reference material (CRM) for the identification and quantification of xanthohumol in raw materials and finished products via HPLC and LC-MS.
• Academic & Life Science Research: A vital tool for in-vitro and in-vivo studies investigating mechanisms of action related to chronic diseases, metabolic syndrome, and oxidative stress.

Basic Information

Product Name	Xanthohumol L
CAS No.	688360-15-8
Molecular Formula	C21H22O5
Molecular Weight	354.40 g/mol
Synonyms	Xanthohumol; (E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one; 2',4,4'-Trihydroxy-6'-methoxy-3'-prenylchalcone; 3'-Prenyl-2',4,4'-trihydroxy-6'-methoxychalcone; Hop chalcone; XN; NSC 407303; Pre-Xanthohumol (related)
EINECS	Contact for details

Quality Control

Our Xanthohumol L is manufactured under strict quality management systems. Each batch is subjected to rigorous identity, purity, and impurity profiling using advanced analytical techniques including HPLC, LC-MS, and NMR spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing specifications for assay, related substances, residual solvents, and heavy metals to ensure compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0% - 98.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.