Description

Pyridine, 3-Ethynyl-5-Methoxy- (9Ci) is a specialized pyridine derivative featuring both an ethynyl and a methoxy substituent, making it a valuable building block for advanced organic synthesis. This compound is engineered to serve as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific heterocyclic scaffolds.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the creation of advanced polymers, conductive materials, or metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: The ethynyl group enables click chemistry (e.g., CuAAC) for labeling and studying biological targets in proteomics and diagnostics.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyridine-based ligands for transition metal catalysis in asymmetric synthesis.
• Research & Development (R&D): A versatile reagent for academic and industrial research exploring new chemical reactions and heterocyclic chemistry.

Basic Information

Product Name	Pyridine, 3-Ethynyl-5-Methoxy- (9Ci)
CAS No.	686768-50-3
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	3-Ethynyl-5-methoxypyridine; 5-Methoxy-3-ethynylpyridine; 3-Ethynyl-5-methoxy-pyridine; 5-Methoxypyridin-3-ylacetylene; Pyridine, 3-ethynyl-5-methoxy-; 3-(Ethynyl)-5-methoxypyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-Ethynyl-5-Methoxy- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for each lot upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.