Description

3-Iodo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other bioactive heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrazolopyridine core.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	3-Iodo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	685522-76-3
Molecular Formula	C7H6IN3
Molecular Weight	259.05 g/mol
Synonyms	1-Methyl-3-iodo-1H-pyrazolo[3,4-b]pyridine; 3-Iodo-1-methylpyrazolo[3,4-b]pyridine; 1-Methyl-3-iodopyrazolo[3,4-b]pyridine; Pyrazolo[3,4-b]pyridine, 3-iodo-1-methyl-; 685522-76-3; 3-Iodo-1-methyl-1H-pyrazolo[3,4-b]pyridin; 1H-Pyrazolo[3,4-b]pyridine, 3-iodo-1-methyl-
EINECS	Contact for details

Quality Control

Our 3-Iodo-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.