Description

2,6-Difluoro-5-Iodo-Nicotinic Acid is a high-value, multi-functional halogenated nicotinic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its halogen-substituted aromatic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	2,6-Difluoro-5-Iodo-Nicotinic Acid
CAS No.	685517-76-4
Molecular Formula	C6H2F2INO2
Molecular Weight	284.99 g/mol
Synonyms	5-Iodo-2,6-difluoronicotinic acid; 2,6-Difluoro-5-iodopyridine-3-carboxylic acid; 3-Carboxy-5-iodo-2,6-difluoropyridine; 685517-76-4; 5-Iodo-2,6-difluoropyridine-3-carboxylic acid; Difluoroiodonicotinic acid; Iododifluoronicotinic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-5-Iodo-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.