Description

8-Azaspiro[4.5]Decane-8-Carboxylic Acid CAS NO 685501-34-2 is a versatile spirocyclic organic acid building block of significant interest in advanced chemical synthesis. Its unique bridged bicyclic structure provides a rigid, three-dimensional framework that is highly valuable for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its spiro structure can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	8-Azaspiro[4.5]Decane-8-Carboxylic Acid
CAS No.	685501-34-2
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	8-Azaspiro[4.5]decane-8-carboxylic acid; 1-Azaspiro[4.5]decane-1-carboxylic acid; 8-Carboxy-8-azaspiro[4.5]decane; Azaspirodecane carboxylic acid; Spirocyclic piperidine-4-carboxylic acid; 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic acid (related); 8-Aza-spiro[4.5]decane-8-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 8-Azaspiro[4.5]Decane-8-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.