Description

1,3,4-Oxadiazol-2(3H)-One, 5-(2-Chlorophenyl)-3-[4-(Trifluoromethyl)-2-Pyridinyl]- is a high-value heterocyclic organic compound featuring a fused oxadiazole and pyridine core, strategically substituted with chlorophenyl and trifluoromethyl groups. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel active ingredients. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring complex, functionalized heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production for clinical trials.

Basic Information

Product Name	1,3,4-Oxadiazol-2(3H)-One, 5-(2-Chlorophenyl)-3-[4-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	685125-49-9
Molecular Formula	C₁₅H₇ClF₃N₃O₂
Molecular Weight	353.68 g/mol
Synonyms	5-(2-Chlorophenyl)-3-[4-(trifluoromethyl)pyridin-2-yl]-1,3,4-oxadiazol-2(3H)-one; 5-(2-Chlorophenyl)-3-(4-(trifluoromethyl)pyridin-2-yl)-1,3,4-oxadiazol-2(3H)-one; 685125-49-9; 2(3H)-Oxadiazolone, 5-(2-chlorophenyl)-3-[4-(trifluoromethyl)-2-pyridinyl]-; 5-(2-Chlorophenyl)-3-(4-trifluoromethylpyridin-2-yl)-1,3,4-oxadiazol-2(3H)-one; 3-(4-(Trifluoromethyl)pyridin-2-yl)-5-(o-chlorophenyl)-1,3,4-oxadiazol-2(3H)-one
EINECS	Contact for details

Quality Control

Our 1,3,4-Oxadiazol-2(3H)-One, 5-(2-Chlorophenyl)-3-[4-(Trifluoromethyl)-2-Pyridinyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.