Description

7-(1,3-Benzodioxol-5-Yl)-2-(3-Methoxyphenyl)[1,2,4]Triazolo[1,5-A]Pyridine-8-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology industries for creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients, leveraging its triazolopyridine core.
• Biochemical Tool Compound: Serves as a reference standard or probe molecule in biochemical assays and target validation studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for pioneering research in heterocyclic chemistry and drug discovery.

Basic Information

Item	Details
Product Name	7-(1,3-Benzodioxol-5-Yl)-2-(3-Methoxyphenyl)[1,2,4]Triazolo[1,5-A]Pyridine-8-Carbonitrile
CAS No.	685108-55-8
Molecular Formula	C21H14N4O3
Molecular Weight	370.36 g/mol
Synonyms	8-Cyano-7-(1,3-benzodioxol-5-yl)-2-(3-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyridine; 2-(3-Methoxyphenyl)-7-(1,3-benzodioxol-5-yl)[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile; [1,2,4]Triazolo[1,5-a]pyridine-8-carbonitrile, 7-(1,3-benzodioxol-5-yl)-2-(3-methoxyphenyl)-; 685108-55-8; 7-(Benzo[d][1,3]dioxol-5-yl)-2-(3-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-(1,3-Benzodioxol-5-Yl)-2-(3-Methoxyphenyl)[1,2,4]Triazolo[1,5-A]Pyridine-8-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.