Description

1H-Pyrrole-2-Carboxylic Acid, 5-[[Hexahydro-4-[4-(Trifluoromethyl)-2-Pyridinyl]-1H-1,4-Diazepin-1-Yl]Sulfonyl]-1-Methyl-, Methyl Ester is a sophisticated heterocyclic building block designed for advanced synthetic chemistry. This compound matters as a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeting complex biological pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to enable the synthesis of next-generation therapeutic candidates.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex, multi-functional structure.
• Chemical Biology Probes: Serves as a precursor for developing specialized molecular probes to study enzyme inhibition and receptor binding.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Agrochemical Research: Potential intermediate in the development of advanced crop protection agents with specific activity.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for pioneering studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrrole-2-Carboxylic Acid, 5-[[Hexahydro-4-[4-(Trifluoromethyl)-2-Pyridinyl]-1H-1,4-Diazepin-1-Yl]Sulfonyl]-1-Methyl-, Methyl Ester
CAS No.	684212-18-8
Molecular Formula	C19H23F3N4O4S
Molecular Weight	460.47 g/mol
Synonyms	Methyl 5-((4-(4-(trifluoromethyl)pyridin-2-yl)hexahydro-1H-1,4-diazepin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxylate; 1-Methyl-5-[(4-[4-(trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl)sulfonyl]-1H-pyrrole-2-carboxylic Acid Methyl Ester; 684212-18-8; 5-((4-(4-(Trifluoromethyl)pyridin-2-yl)hexahydro-1H-1,4-diazepin-1-yl)sulfonyl)-1-methyl-1H-pyrrole-2-carboxylic acid methyl ester; Pyrrole-2-carboxylic acid derivative; Trifluoromethylpyridinyl diazepine sulfonyl pyrrole ester.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical R&D and cGMP applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.