Description

6-(1,4-Diazepan-1-Yl)Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research and development of novel psychoactive substances and neuropharmaceuticals due to its diazepane moiety.
• Oncology Research: Investigated as a building block for kinase inhibitors and other targeted cancer therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for chemical biology and pharmacological studies.

Basic Information

Product Name	6-(1,4-Diazepan-1-Yl)Nicotinonitrile
CAS No.	683274-59-1
Molecular Formula	C11H13N5
Molecular Weight	215.26 g/mol
Synonyms	6-(1,4-Diazepan-1-yl)nicotinonitrile; 6-(1,4-Diazepan-1-yl)-3-pyridinecarbonitrile; 3-Cyano-6-(1,4-diazepan-1-yl)pyridine; 6-(1,4-Diazepan-1-yl)pyridine-3-carbonitrile; Nicotinonitrile, 6-(1,4-diazepan-1-yl)-; Pyridine-3-carbonitrile, 6-(1,4-diazepan-1-yl)-
EINECS	Contact for details

Quality Control

Our 6-(1,4-Diazepan-1-Yl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.