Description

(S)-1-(3-Bromopyridin-2-Yl)-3-Methylpiperazine is a high-purity chiral piperazine derivative, serving as a critical building block in modern organic synthesis. Its value lies in its role as a sophisticated intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential CNS drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed as a molecular scaffold or probe in medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	(S)-1-(3-Bromopyridin-2-Yl)-3-Methylpiperazine
CAS No.	683241-56-7
Molecular Formula	C10H14BrN3
Molecular Weight	256.14 g/mol
Synonyms	(S)-3-Methyl-1-(3-bromo-2-pyridinyl)piperazine; (S)-1-(3-Bromo-2-pyridyl)-3-methylpiperazine; (S)-3-Methyl-1-(3-bromopyridin-2-yl)piperazine; 683241-56-7; (S)-enantiomer of 1-(3-Bromopyridin-2-yl)-3-methylpiperazine; (S)-1-(3-Bromo-2-pyridinyl)-3-methylpiperazine; (S)-1-(3-Bromopyridin-2-yl)-3-methylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-(3-Bromopyridin-2-Yl)-3-Methylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and pharmaceutical development. Quality is verified through comprehensive analytical techniques including HPLC, GC, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.