Description

4-Isoxazolecarboxylicacid,5-(Bromomethyl)-3-(2-Chlorophenyl)-,Methylester(9Ci) CAS NO 682352-82-5 is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound matters because its unique structure, featuring reactive bromomethyl and ester groups on an isoxazole core, enables the efficient construction of complex molecules for pharmaceutical and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole moiety.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Isoxazolecarboxylicacid,5-(Bromomethyl)-3-(2-Chlorophenyl)-,Methylester(9Ci)
CAS No.	682352-82-5
Molecular Formula	C12H9BrClNO3
Molecular Weight	330.56 g/mol
Synonyms	Methyl 5-(bromomethyl)-3-(2-chlorophenyl)-1,2-oxazole-4-carboxylate; 3-(2-Chlorophenyl)-5-(bromomethyl)isoxazole-4-carboxylic acid methyl ester; 5-(Bromomethyl)-3-(2-chlorophenyl)-4-isoxazolecarboxylic acid methyl ester; 682352-82-5; AI3-52715; AKOS040751195; SCHEMBL21805579; ZINC000253919777
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarboxylicacid,5-(Bromomethyl)-3-(2-Chlorophenyl)-,Methylester(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.