Description

1-Boc-Amino-2-Vinylcyclopropanecarboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropane and vinyl functionalities. This compound is essential for the synthesis of complex bioactive molecules, particularly in the development of novel protease inhibitors and other therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially protease inhibitors and antiviral agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide structures and enhance metabolic stability.
• Process Chemistry Development: Employed in route scouting and scale-up studies for active pharmaceutical ingredient (API) manufacturing.
• Bioconjugation Chemistry: The vinyl group offers a handle for click chemistry and other bio-orthogonal conjugation strategies.

Basic Information

Product Name	1-Boc-Amino-2-Vinylcyclopropanecarboxylic Acid Ethyl Ester
CAS No.	681807-59-0
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	Ethyl 1-[(tert-butoxycarbonyl)amino]-2-vinylcyclopropane-1-carboxylate; 1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid Ethyl Ester; 1-Boc-amino-2-vinylcyclopropanecarboxylic acid ethyl ester; 1-N-Boc-2-vinylcyclopropanecarboxylic acid ethyl ester; 2-Vinyl-1-Boc-aminocyclopropanecarboxylic Acid Ethyl Ester; (1-((tert-Butoxycarbonyl)amino)-2-vinylcyclopropyl)formic Acid Ethyl Ester; BOC-AVCP-OEt
EINECS	Contact for details

Quality Control

Our 1-Boc-Amino-2-Vinylcyclopropanecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.