Description

Pyridine, 2-Fluoro-4-(1-Pentynyl)- (9Ci) is a specialized fluorinated pyridine derivative featuring an alkynyl side chain, making it a valuable building block in advanced organic synthesis. This compound is designed for applications requiring precise molecular architecture, offering a unique combination of a fluorine atom and a terminal alkyne functional group for selective coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for functionalized ligands in catalysis or as a monomer for specialty polymers with tailored electronic properties.
• Chemical Biology Probes: The alkyne group enables click chemistry reactions (e.g., CuAAC) for bioconjugation and labeling applications in probe and diagnostic agent development.
• Cross-Coupling Reactions: Utilized in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl and conjugated systems.

Basic Information

Product Name	Pyridine, 2-Fluoro-4-(1-Pentynyl)- (9Ci)
CAS No.	681262-23-7
Molecular Formula	C10H8FN
Molecular Weight	161.18 g/mol
Synonyms	2-Fluoro-4-(pent-1-yn-1-yl)pyridine; 4-(1-Pentynyl)-2-fluoropyridine; 2-Fluoro-4-pent-1-ynylpyridine; 2-Fluoro-4-(1-pentynyl)pyridine; Pyridine, 2-fluoro-4-(1-pentynyl)-
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Fluoro-4-(1-Pentynyl)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development. We employ advanced analytical techniques including NMR, HPLC, and GC-MS for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.