Description

[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Methanol CAS NO 681260-50-4 is a high-value fluorinated pyridine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its molecular structure, featuring a trifluoromethyl group and a hydroxymethyl side chain, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated pyridine chemistry.

Basic Information

Product Name	[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Methanol
CAS No.	681260-50-4
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	(6-(Trifluoromethyl)-2-pyridinyl)methanol; 2-(Hydroxymethyl)-6-(trifluoromethyl)pyridine; 3-Pyridinemethanol, 2-methyl-6-(trifluoromethyl)-; [2-Methyl-6-(trifluoromethyl)-3-pyridyl]methanol; 6-(Trifluoromethyl)pyridine-2-methanol; 2-Methyl-6-trifluoromethyl-3-pyridinemethanol
EINECS	Contact for details

Quality Control

Our [2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Methanol is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.