Description

Spiro[2.5]Octane-1-Carboxylic Acid, (1R)- (9Ci) is a chiral spirocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure, which provides a rigid scaffold for constructing complex molecules with defined stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated, spirocyclic ligand frameworks for transition metal catalysis.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with unique modes of action.
• Material Science Monomer: Potential use in creating polymers with specific chiral or rigid structural properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, exploring new spiroannulation and functionalization reactions.

Basic Information

Product Name	Spiro[2.5]Octane-1-Carboxylic Acid, (1R)- (9Ci)
CAS No.	680618-96-6
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R)-Spiro[2.5]octane-1-carboxylic acid; (R)-Spiro[2.5]octane-1-carboxylic acid; (1R)-1-Carboxyspiro[2.5]octane; (R)-1-Carboxyspiro[2.5]octane; (1R)-Spiro[2.5]octane-1-carboxylic acid (9CI); (R)-Spiro[2.5]octane-1-carboxylic acid (9CI); Spiro[2.5]octane-1-carboxylic acid, (1R)-; (R)-1-Spiro[2.5]octanecarboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octane-1-Carboxylic Acid, (1R)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical purity, verified by techniques such as HPLC, GC, and NMR. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.