Description

Methanesulfonic Acid 2-Chloropyridin-4-Ylmethyl Ester CAS NO 680569-47-5 is a specialized organic synthesis intermediate, specifically a mesylate ester derivative of a chloropyridine scaffold. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), novel crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with the chloropyridine moiety.
• Chemical Research & Development: Used in academic and industrial labs for method development, scaffold diversification, and creating compound libraries for high-throughput screening.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in cross-coupling and other catalytic reactions.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials due to its reactive ester group.

Basic Information

Product Name	Methanesulfonic Acid 2-Chloropyridin-4-Ylmethyl Ester
CAS No.	680569-47-5
Molecular Formula	C8H10ClNO3S
Molecular Weight	235.69 g/mol
Synonyms	2-Chloro-4-(methanesulfonyloxymethyl)pyridine; (2-Chloropyridin-4-yl)methyl methanesulfonate; 4-(Chloromethyl)-2-pyridinyl methanesulfonate; Mesylate ester of 2-chloro-4-pyridinemethanol; 2-Chloro-4-pyridylmethyl methanesulfonate; 680569-47-5; 2-Chloro-4-(methylsulfonyloxymethyl)pyridine
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid 2-Chloropyridin-4-Ylmethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.