Description

2-Chloro-n-Pyridin-3-Ylisonicotinamide CAS NO 680217-96-3 is a specialized heterocyclic compound featuring a pyridine core functionalized with chloro and isonicotinamide groups. This molecular architecture makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in creating novel therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides due to its bioactive heterocyclic structure.
• Material Science: Serves as a precursor for ligands in catalytic systems or for creating functionalized polymers with specific electronic properties.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying biological processes and target validation.

Basic Information

Product Name	2-Chloro-n-Pyridin-3-Ylisonicotinamide
CAS No.	680217-96-3
Molecular Formula	C11H8ClN3O
Molecular Weight	233.66 g/mol
Synonyms	2-Chloro-N-(pyridin-3-yl)isonicotinamide; 3-Pyridinamine, N-(2-chloro-4-pyridinyl)-; N-(3-Pyridinyl)-2-chloro-4-pyridinecarboxamide; 2-Chloro-N-(3-pyridinyl)isonicotinamide; 2-Chloro-N-(3-pyridyl)isonicotinamide; 2-Chloro-N-(pyridin-3-yl)pyridine-4-carboxamide; 680217-96-3; 2-Chloro-N-(3-pyridinyl)-4-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Pyridin-3-Ylisonicotinamide is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.