Description

Phenyl 2,6-Dichloro-5-Fluoronicotinate is a high-purity fluorinated pyridine derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new fluorinated compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs containing fluoropyridine motifs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Chemical Research & Development: Serves as a versatile substrate for cross-coupling reactions, nucleophilic substitutions, and other transformations in medicinal and process chemistry.
• Material Science Precursor: Potential intermediate for the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorinated aromatic structures.

Basic Information

Product Name	Phenyl 2,6-Dichloro-5-Fluoronicotinate
CAS No.	680217-90-7
Molecular Formula	C12H6Cl2FNO2
Molecular Weight	286.09 g/mol
Synonyms	Phenyl 2,6-dichloro-5-fluoropyridine-3-carboxylate; 5-Fluoro-2,6-dichloronicotinic acid phenyl ester; 3-Pyridinecarboxylic acid, 2,6-dichloro-5-fluoro-, phenyl ester; 2,6-Dichloro-5-fluoro-3-pyridinecarboxylic acid phenyl ester; Phenyl 5-fluoro-2,6-dichloronicotinate
EINECS	Contact for details

Quality Control

Our Phenyl 2,6-Dichloro-5-Fluoronicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.