Description

2,6-Dichloro-5-Fluoro-n-Pyridin-3-Ylnicotinamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its fluorinated pyridine core.
• Chemical Synthesis: Acts as a versatile precursor for creating complex heterocyclic compounds in medicinal chemistry.
• Material Science: Potential application in the research of organic electronic materials and ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	2,6-Dichloro-5-Fluoro-n-Pyridin-3-Ylnicotinamide
CAS No.	680217-89-4
Molecular Formula	C11H6Cl2FN3O
Molecular Weight	286.09 g/mol
Synonyms	2,6-Dichloro-5-fluoronicotinamide; 3-Pyridinecarboxamide, 2,6-dichloro-5-fluoro-; 2,6-Dichloro-5-fluoro-3-pyridinecarboxamide; 5-Fluoro-2,6-dichloronicotinamide; 680217-89-4; Nicotinamide, 2,6-dichloro-5-fluoro-; 2,6-Dichloro-5-fluoropyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-5-Fluoro-n-Pyridin-3-Ylnicotinamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.