Description

n-[4-(tert-Butyl)Phenyl]-2,6-Dichloro-5-Fluoronicotinamide is a high-purity, specialized organic compound belonging to the nicotinamide derivative class. This chemical is a critical advanced pharmaceutical intermediate (API intermediate) valued for its precise molecular structure, which is essential for synthesizing complex active ingredients. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Research: Used in the development and testing of new pesticides and herbicides due to its halogenated pyridine core.
• Material Science: Acts as a precursor for functional materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules, leveraging the reactivity of its dichloro and fluoro substituents.
• Biochemical Research: Potential use as a probe or inhibitor in biochemical studies targeting specific enzymatic pathways.

Basic Information

Item	Detail
Product Name	n-[4-(tert-Butyl)Phenyl]-2,6-Dichloro-5-Fluoronicotinamide
CAS No.	680217-83-8
Molecular Formula	C16H15Cl2FN2O
Molecular Weight	341.21 g/mol
Synonyms	2,6-Dichloro-5-fluoro-N-[4-(1,1-dimethylethyl)phenyl]-3-pyridinecarboxamide; 5-Fluoro-2,6-dichloro-N-[4-(tert-butyl)phenyl]nicotinamide; N-(4-tert-Butylphenyl)-2,6-dichloro-5-fluoronicotinamide; 680217-83-8; tert-Butylphenyl dichlorofluoronicotinamide; Nicotinamide, N-[4-(1,1-dimethylethyl)phenyl]-2,6-dichloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our n-[4-(tert-Butyl)Phenyl]-2,6-Dichloro-5-Fluoronicotinamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.