Description

2,6-Dichloro-5-Fluoro-n-(Thien-2-Ylmethyl)Nicotinamide is a high-value pharmaceutical intermediate and chemical building block. Its molecular structure, featuring a nicotinamide core with halogen and thienylmethyl substituents, makes it a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents. CAS No. 680217-82-7.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in areas requiring halogenated heterocycles.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its specific halogen pattern contributes to biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Manufacturing: Employed in the multi-step synthesis of complex target molecules for clinical and commercial pharmaceutical production.
• Material Science Precursor: Potential use in the synthesis of specialized ligands or functional materials for electronic or catalytic applications.

Basic Information

Product Name	2,6-Dichloro-5-Fluoro-n-(Thien-2-Ylmethyl)Nicotinamide
CAS No.	680217-82-7
Molecular Formula	C12H7Cl2FN2OS
Molecular Weight	317.17 g/mol
Synonyms	2,6-Dichloro-5-fluoro-N-(thiophen-2-ylmethyl)nicotinamide; 2,6-Dichloro-5-fluoro-N-[(thiophen-2-yl)methyl]pyridine-3-carboxamide; 680217-82-7; Nicotinamide, 2,6-dichloro-5-fluoro-N-(2-thienylmethyl)-; 5-Fluoro-2,6-dichloro-N-(thiophen-2-ylmethyl)nicotinamide; N-(Thiophen-2-ylmethyl)-2,6-dichloro-5-fluoronicotinamide
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-5-Fluoro-n-(Thien-2-Ylmethyl)Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.