Description

2-Chloro-5-(5-[(4-Chlorobenzyl)Thio]-4-[3-(Trifluoromethyl)Phenyl]-4H-1,2,4-Triazol-3-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure containing a triazole core. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Industrial and research chemists in the pharmaceutical, agrochemical, and advanced materials sectors need this precise chemical for developing next-generation compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its triazole moiety for biological activity.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential application in the synthesis of specialty polymers or ligands for catalytic systems due to its stable heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Detail
Product Name	2-Chloro-5-(5-[(4-Chlorobenzyl)Thio]-4-[3-(Trifluoromethyl)Phenyl]-4H-1,2,4-Triazol-3-Yl)Pyridine
CAS No.	680216-98-2
Molecular Formula	C21H13Cl2F3N4S
Molecular Weight	481.32 g/mol
Synonyms	2-Chloro-5-{5-[(4-chlorophenyl)methylsulfanyl]-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}pyridine; 680216-98-2; 4H-1,2,4-Triazol-3-ylpyridine derivative; 5-[(4-Chlorobenzyl)thio]-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl-2-chloropyridine; Triazole-pyridine intermediate
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(5-[(4-Chlorobenzyl)Thio]-4-[3-(Trifluoromethyl)Phenyl]-4H-1,2,4-Triazol-3-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.