Description

Methyl 6-Amino-5-Iodo-2-Methylnicotinate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized pyridine core.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced organic electronic materials and dyes.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Academic & Contract Research: A vital reagent for methodological studies and custom synthesis projects in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl 6-Amino-5-Iodo-2-Methylnicotinate
CAS No.	680208-83-7
Molecular Formula	C8H9IN2O2
Molecular Weight	292.07 g/mol
Synonyms	5-Iodo-6-amino-2-methylnicotinic acid methyl ester; Methyl 5-iodo-6-amino-2-picolinate; 2-Picolinic acid, 6-amino-5-iodo-2-methyl-, methyl ester; 6-Amino-5-iodo-2-methylnicotinic acid methyl ester; Methyl 2-methyl-6-amino-5-iodonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-5-Iodo-2-Methylnicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥97% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system supports compliance with global regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.