Description

4-Pentenoicacid,2-Amino-2-(2-Propynyl)-,Methylester,(-)-(9Ci) is a chiral, non-natural amino acid derivative featuring both a pentenoic acid ester and a propargyl group, making it a versatile and valuable synthetic building block. This compound matters for its unique bifunctional reactivity, enabling its use in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide mimetics, and the development of novel bioactive compounds. The product is supplied with CAS number 680189-75-7.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic disorders.
• Peptidomimetics & Bio-conjugation: The amino acid core and reactive alkyne/alkene handles make it ideal for creating peptide analogs and for site-specific bioconjugation via click chemistry.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific chiral centers for optimal activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and protein-protein interactions.
• Material Science: Acts as a monomer or cross-linker precursor for specialty polymers with tailored properties, such as hydrogels or smart materials.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in catalytic asymmetric reactions to induce stereoselectivity.

Basic Information

Product Name	4-Pentenoicacid,2-Amino-2-(2-Propynyl)-,Methylester,(-)-(9Ci)
CAS No.	680189-75-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(-)-2-Amino-2-(2-propynyl)-4-pentenoic acid methyl ester; Methyl (2S)-2-amino-2-(prop-2-yn-1-yl)pent-4-enoate; (S)-2-Amino-2-(prop-2-ynyl)pent-4-enoic acid methyl ester; 2-Amino-2-(2-propynyl)-4-pentenoic acid methyl ester, (-)-; L-2-Amino-2-(prop-2-yn-1-yl)pent-4-enoic acid methyl ester; (S)-Methyl 2-amino-2-(prop-2-yn-1-yl)pent-4-enoate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 4-Pentenoicacid,2-Amino-2-(2-Propynyl)-,Methylester,(-)-(9Ci) is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and impurity profiles are available upon request. We adhere to cGMP principles for manufacturing to ensure batch-to-batch consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.