Description

tert-Butyl 2-Chloro-7,8-Dihydro-5H-Pyrido[2,3-B]Azepine-9(6H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used for constructing fused polycyclic nitrogen-containing heterocycles, which are privileged structures in medicinal chemistry.
• Research & Development (R&D): Essential material for academic and industrial research programs focused on novel kinase inhibitors or receptor modulators.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial manufacturing of potential APIs.
• Custom Synthesis: Serves as a starting point for the preparation of specialized analogs and derivatives for biological screening.

Basic Information

Product Name	tert-Butyl 2-Chloro-7,8-Dihydro-5H-Pyrido[2,3-B]Azepine-9(6H)-Carboxylate
CAS No.	679392-25-7
Molecular Formula	C15H21ClN2O2
Molecular Weight	296.79 g/mol
Synonyms	2-Chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepine-9-carboxylic acid tert-butyl ester; tert-Butyl 2-chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepine-9-carboxylate; 9-Boc-2-chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepine; 679392-25-7; 2-Chloro-9-(tert-butoxycarbonyl)-6,7,8,9-tetrahydro-5H-pyrido[2,3-b]azepine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-7,8-Dihydro-5H-Pyrido[2,3-B]Azepine-9(6H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Individual impurity ≤1.0%
Total Impurities	≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.