Description

4-Cyclopentene-1,3-Diol, 1-[3-(Trimethylsilyl)-2-Propynyl]- (9Ci) is a specialized organosilicon building block featuring a unique cyclopentene diol core functionalized with a trimethylsilyl-protected propargyl group. This compound is valued for its dual reactivity, serving as a versatile intermediate in advanced organic synthesis and materials science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex cyclic structures.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its functional group diversity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for synthesizing specialty polymers, silicones, and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and other fine chemicals via click chemistry or other coupling reactions.
• Ligand & Catalyst Development: Potential precursor for creating novel chiral ligands or organometallic catalysts due to its diol and alkyne functionalities.

Basic Information

Product Name	4-Cyclopentene-1,3-Diol, 1-[3-(Trimethylsilyl)-2-Propynyl]- (9Ci)
CAS No.	678143-40-3
Molecular Formula	C11H18O2Si
Molecular Weight	210.35 g/mol
Synonyms	1-[3-(Trimethylsilyl)-2-propynyl]-4-cyclopentene-1,3-diol; 1-(3-Trimethylsilylprop-2-yn-1-yl)cyclopent-4-ene-1,3-diol; 4-Cyclopentene-1,3-diol, 1-[3-(trimethylsilyl)-2-propynyl]-; TMS-Propargyl Cyclopentenediol; (1R,3S)-1-[3-(Trimethylsilyl)prop-2-yn-1-yl]cyclopent-4-ene-1,3-diol (stereoisomer); CAS 678143-40-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Quality is verified through advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.