Description

1,3-Dioxaspiro[4.4]Nonan-6-Ol,2,2,4-Trimethyl-7-Methylene-,(4R,5S,6R)-(9Ci) is a high-purity, stereochemically defined spirocyclic compound featuring a unique 1,3-dioxolane ring fused to a cyclohexane system. This specific chiral intermediate is valued for its structural complexity and functional groups, which make it a critical building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its spirocyclic structure can contribute to novel modes of action and improved environmental profiles.
• Asymmetric Catalysis Ligand Precursor: The molecule's defined stereocenters and oxygenated framework make it a potential precursor for synthesizing novel chiral ligands or organocatalysts.
• Flavor & Fragrance Chemistry: Acts as an intermediate for creating sophisticated, musk-like or woody odorants due to its complex, polycyclic nature.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties derived from its rigid spiro structure.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for complex molecule construction, serving as a benchmark compound.

Basic Information

Product Name	1,3-Dioxaspiro[4.4]Nonan-6-Ol,2,2,4-Trimethyl-7-Methylene-,(4R,5S,6R)-(9Ci)
CAS No.	677752-15-7
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(4R,5S,6R)-2,2,4-Trimethyl-7-methylene-1,3-dioxaspiro[4.4]nonan-6-ol; (4R,5S,6R)-2,2,4-Trimethyl-7-methylidene-1,3-dioxaspiro[4.4]nonan-6-ol; 1,3-Dioxaspiro[4.4]nonan-6-ol, 2,2,4-trimethyl-7-methylene-, (4R,5S,6R)-; Spirocyclic dioxolane alcohol intermediate; (4R,5S,6R)-Trimethylmethylene-dioxaspiro[4.4]nonanol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.