Description

1,3-Dioxaspiro[4.4]Nonan-6-Ol,2,2,4-Trimethyl-7-Methylene-,(4S,5S,6S)-(9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique fused-ring structure with defined stereocenters makes it a critical component for constructing complex molecular architectures with high precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials. The CAS number for this product is 677752-05-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Material Science: A building block for creating specialized polymers and liquid crystals with unique optical or mechanical properties.
• Academic & R&D: Employed in methodological studies and total synthesis projects in university and industrial research laboratories.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, stereochemically pure odorants and flavoring agents.

Basic Information

Product Name	1,3-Dioxaspiro[4.4]Nonan-6-Ol,2,2,4-Trimethyl-7-Methylene-,(4S,5S,6S)-(9Ci)
CAS No.	677752-05-5
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(4S,5S,6S)-2,2,4-Trimethyl-7-methylene-1,3-dioxaspiro[4.4]nonan-6-ol; (4S,5S,6S)-2,2,4-Trimethyl-7-methylidene-1,3-dioxaspiro[4.4]nonan-6-ol; 1,3-Dioxaspiro[4.4]nonan-6-ol, 2,2,4-trimethyl-7-methylene-, (4S,5S,6S)-; Spirocyclic dioxolane alcohol; Chiral spiroketal derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxaspiro[4.4]Nonan-6-Ol,2,2,4-Trimethyl-7-Methylene-,(4S,5S,6S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP and ISO compliant documentation for regulated industry needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and prolonged exposure to air; containers should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.