Description

Spiro[1,3-Dioxolane-4,2'-[6]Oxabicyclo[3.1.0]Hexane], 2,2,5,5-Tetramethyl-, (1S,2R,5R,5S)- (9Ci) is a high-purity, stereochemically defined spirocyclic compound with the CAS number 677751-84-7. This molecule serves as a versatile chiral building block and intermediate in advanced organic synthesis, valued for its rigid, three-dimensional structure. It is primarily sought by pharmaceutical R&D and fine chemical sectors for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Employed as a sophisticated ligand or scaffold in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Used in the synthesis of novel, biologically active compounds for crop protection and pest management.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Serves as an intermediate for creating complex, stereospecific odorants and flavoring agents.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and the construction of complex natural product analogs.

Basic Information

Product Name	Spiro[1,3-Dioxolane-4,2'-[6]Oxabicyclo[3.1.0]Hexane], 2,2,5,5-Tetramethyl-, (1S,2R,5R,5S)- (9Ci)
CAS No.	677751-84-7
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	(1S,2R,5R,5S)-2,2,5,5-Tetramethylspiro[1,3-dioxolane-4,2'-[6]oxabicyclo[3.1.0]hexane]; Tetramethyl Spiro Dioxolane Oxabicyclohexane; (1S,2R,5R,5S)-Isomer of CAS 677751-84-7; Spirocyclic Dioxolane Ether; Chiral Spiroketal; Oxaspiro Compound; Bicyclic Acetal Intermediate
EINECS	Contact for details

Quality Control

Our production of Spiro[1,3-Dioxolane-4,2'-[6]Oxabicyclo[3.1.0]Hexane], 2,2,5,5-Tetramethyl-, (1S,2R,5R,5S)- (9Ci) adheres to stringent cGMP and ISO 9001 guidelines to ensure batch-to-batch consistency and traceability. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We provide custom synthesis and purity grades (from technical to >98% HPLC) to meet specific research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.