Description

2-Morpholino-5-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional chemical intermediate featuring a morpholine ring and a trifluoromethyl group. This unique structure makes it a critical building block for the synthesis of advanced pharmaceutical compounds and agrochemicals, offering enhanced metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	2-Morpholino-5-(Trifluoromethyl)Benzonitrile
CAS No.	677749-94-9
Molecular Formula	C12H11F3N2O
Molecular Weight	256.23 g/mol
Synonyms	5-(Trifluoromethyl)-2-morpholinobenzonitrile; 2-Morpholin-4-yl-5-(trifluoromethyl)benzonitrile; 4-[4-Cyano-2-(trifluoromethyl)phenyl]morpholine; 2-Morpholino-α,α,α-trifluoro-p-tolunitrile; Benzonitrile, 2-morpholino-5-(trifluoromethyl)-; 677749-94-9
EINECS	Contact for details

Quality Control

We supply 2-Morpholino-5-(Trifluoromethyl)Benzonitrile in high-purity grades suitable for research and commercial-scale synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.