Description

5-Bromo-4-Methylnicotinic Acid is a halogenated derivative of nicotinic acid, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in providing a functionalized pyridine scaffold that is critical for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for drug discovery, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	5-Bromo-4-Methylnicotinic Acid
CAS No.	677702-58-8
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	5-Bromo-4-methylpyridine-3-carboxylic acid; 3-Carboxy-5-bromo-4-methylpyridine; 4-Methyl-5-bromonicotinic acid; 5-Bromo-4-methyl-3-pyridinecarboxylic acid; 5-Bromo-4-methyl-nicotinic acid; 677702-58-8; Nicotinic acid, 5-bromo-4-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates, and we can accommodate specific customer requirements for pharmaceutical or advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.