Description

2-(Biphenyl-4-Carbonyl)-3-Oxo-Butyric Acid Ethyl Ester is a high-value, specialized organic intermediate characterized by its biphenyl and β-keto ester functional groups. This compound is crucial for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles and natural product analogs via its reactive carbonyl groups.
• Ligand and Catalyst Development: Utilized in the preparation of novel chelating ligands for metal-catalyzed reactions.

Basic Information

Product Name	2-(Biphenyl-4-Carbonyl)-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	677326-75-9
Molecular Formula	C21H20O4
Molecular Weight	336.38 g/mol
Synonyms	Ethyl 2-(4-biphenylcarbonyl)-3-oxobutanoate; Ethyl 2-(biphenyl-4-carbonyl)-3-oxobutanoate; 3-Oxo-2-[(1,1'-biphenyl)-4-ylcarbonyl]butyric Acid Ethyl Ester; 4'-Acetylbiphenyl-4-carboxylic Acid Ethyl Ester (tautomeric form); Biphenyl-4-carbonyl acetoacetate ethyl ester; [4-(Ethoxycarbonyl)-3-oxobutanoyl]biphenyl
EINECS	Contact for details

Quality Control

Every batch of 2-(Biphenyl-4-Carbonyl)-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.