Description

1'-Benzyl 1-tert-Butyl Spiro[Indoline-3,4'-Piperidine]-1,1'-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Drug Discovery Research: Serves as a versatile scaffold for medicinal chemists to develop new chemical entities (NCEs) with potential therapeutic activity.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for potential API manufacturing.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1'-Benzyl 1-tert-Butyl Spiro[Indoline-3,4'-Piperidine]-1,1'-Dicarboxylate
CAS No.	676607-30-0
Molecular Formula	C25H30N2O4
Molecular Weight	422.52 g/mol
Synonyms	1-tert-Butyl 1'-benzyl spiro[indoline-3,4'-piperidine]-1,1'-dicarboxylate; 1,1'-Dicarboxylic acid, 1-(1,1-dimethylethyl) 1'-(phenylmethyl) ester, spiro[indoline-3,4'-piperidine]-; Spiro[indoline-3,4'-piperidine]-1,1'-dicarboxylic acid, 1-(1,1-dimethylethyl) 1'-(phenylmethyl) ester; 1'-Benzyl 1-tert-butyl spiro[indoline-3,4'-piperidine]-1,1'-dicarboxylate; tert-Butyl 1'-benzyl-1,1'-dioxo-1λ⁶,1'λ⁶-spiro[indoline-3,4'-piperidine]-1-carboxylate (alternative representation); BOC-Spiro Indoline Piperidine Benzyl Ester; CAS 676607-30-0.
EINECS	Contact for details

Quality Control

Our 1'-Benzyl 1-tert-Butyl Spiro[Indoline-3,4'-Piperidine]-1,1'-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.