Description

n-(5-Iodo-6-Methyl-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity, specialized organic intermediate featuring a halogenated pyridine core with a sterically hindered amide group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific structural motifs for bioactivity or material properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in developing novel pesticides or herbicides, where the iodopyridine structure can contribute to specific biological activity.
• Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or cellular processes.
• Material Science: Potential monomer or additive in the development of advanced polymers with specific electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) fulfilling custom synthesis projects for client-specific molecules.

Basic Information

Product Name	n-(5-Iodo-6-Methyl-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	676588-16-2
Molecular Formula	C11H15IN2O
Molecular Weight	318.16 g/mol
Synonyms	2,2-Dimethyl-N-(5-iodo-6-methyl-2-pyridinyl)propanamide; 5-Iodo-6-methyl-N-pivaloylpyridin-2-amine; Pivalamide, N-(5-iodo-6-methyl-2-pyridinyl)-; N-(5-Iodo-6-methylpyridin-2-yl)pivalamide; 2-Pyridinamine, 5-iodo-6-methyl-N-(2,2-dimethyl-1-oxopropyl)-; 676588-16-2; 5-Iodo-6-methyl-2-(pivalamido)pyridine
EINECS	Contact for details

Quality Control

Our n-(5-Iodo-6-Methyl-Pyridin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.